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    Introduction from LifeArc

    Explore Our Job Sims

    Tasks in this program

    Intro & Scenario
    Meet your team members and learn about your project goals.
    Your role

    As an associate scientist in our Chemical Biology team, you are working on the development of a new proteolysis-targeting chimeras (PROTAC) against a cancer-relevant protein. PROTACs are a recently developed class of designer molecules that promote the degradation of specific proteins in the cell by targeting them to the cellular organelle known as the proteasome. The modular structure of PROTACs and their potential to target molecules that are out of reach for classic inhibitors and antibodies make them promising drug candidates for a broad range of diseases. 

    In this simulation, you will: 

    • Design candidate PROTAC molecules against a cancer-relevant protein
    • Learn about click chemistry and how it enables efficient and versatile PROTAC synthesis
    • Interpret data from PROTAC validation experiments
    • Summarise your findings in a presentation and deliver it in a video recording
    Your goal
    • Determine a lead PROTAC candidate to put forward for further validation
    • Present your research findings to the team
    Chemistry

    Why complete this job simulation

    A risk-free way to experience work on the job with us at LifeArc. Practise your skills, gain new knowledge, and test your enthusiasm for relevant tasks.
    Self-paced5-6 hoursNo gradesNo assessmentsIntermediate

    Welcome to the LifeArc Chemistry Job Simulation! We are thrilled to have you here.

    The Chemical Biology team focuses on the design and synthesis of drug-like molecules for the treatment of various diseases.

    During this programme, you will get the opportunity to step into the shoes of a LifeArc associate scientist and complete tasks that replicate the work that our Chemical Biology team does every day. You’ll gain knowledge and skills in:
    - Designing and synthesising bioactive compounds
    - Interpreting data from biochemical validation experiments
    - Communicating project findings

    We hope this programme provides a great resource for you to enhance and strengthen your CV as you explore career options and a potential career at LifeArc.

    Skills that will help before starting:
    Undergraduate level organic chemistry
    Undergraduate level molecular biology
    Skills you will learn and practice:
    Chemical Analysis
    Molecular Design
    Research Design
    Chemical Modeling
    Chemical Synthesis
    Data Interpretation
    Research Presentation
    Research Communication
    Presentation Preparation

    How it works

    Complete tasks guided by pre-recorded videos and example answers from our team at LifeArc. No live sessions, all self-paced.
    Earn a certificate and add it to your CV and LinkedIn as an extracurricular activity.
    Stand out in job applications. Show familiarity with real-life topics, tasks and environment of a chemical biology R&D lab.
    Chemistry
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    Get Career Ready

    Complete work that simulates life on the job. 5-6 hours and self-paced.
    Stand out in your application to LifeArc. Show us your knowledge and motivation for the job.

    Get Career Ready

    Complete work that simulates life on the job. 5-6 hours and self-paced.
    Stand out in your application to LifeArc. Show us your knowledge and motivation for the job.
    Company Logo

    Chemistry

    Design, synthesis and validation of bioactive compounds

    Life Sciences Free 350+ 5 Star Reviews