I enjoyed how the simulation reflected real-world chemistry work. It gave me the opportunity to apply scientific thinking, analyze data, solve practical problems, and make decisions based on evidence. I also liked learning how chemistry is used to address real challenges in a professional environment, which strengthened my interest in pursuing a career in science.
I really liked how the program simulated real-life drug discovery work, allowing me to move step by step from PROTAC design to synthesis, data analysis, and presentation. It helped me build confidence in both scientific thinking and communication while applying concepts in a practical, industry-relevant context.
It was very informative , and it taught me so much about processes I’ve never heard before. I feel more confident applying for roles based in this chemistry. It guided me very well , and has improved my chemical knowledge and also my presentation skills. It has been such a value experience and I am really glad I signed up for it .
Background context and your project team
As an associate scientist in our Chemical Biology team, you are working on the development of a new proteolysis-targeting chimeras (PROTAC) against a cancer-relevant protein. PROTACs are a recently developed class of designer molecules that promote the degradation of specific proteins in the cell by targeting them to the cellular organelle known as the proteasome. The modular structure of PROTACs and their potential to target molecules that are out of reach for classic inhibitors and antibodies make them promising drug candidates for a broad range of diseases.
In this simulation, you will:
Welcome to the LifeArc Chemistry Job Simulation! We are thrilled to have you here.
The Chemical Biology team focuses on the design and synthesis of drug-like molecules for the treatment of various diseases.
During this programme, you will get the opportunity to step into the shoes of a LifeArc associate scientist and complete tasks that replicate the work that our Chemical Biology team does every day. You’ll gain knowledge and skills in:
- Designing and synthesising bioactive compounds
- Interpreting data from biochemical validation experiments
- Communicating project findings
We hope this programme provides a great resource for you to enhance and strengthen your CV as you explore career options and a potential career at LifeArc.
Design, synthesis and validation of bioactive compounds
